Workflow

Bio-Retinol Fusion Complex™

Project BRF-02: Irritation-free retinol alternative with superior anti-aging performance

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Project context

Bio-Retinol Fusion Complex™

Irritation-free retinol alternative targeting ≥25% collagen boost, 20% wrinkle reduction @ 8 weeks, superior barrier repair, and sustainability (3 kg CO₂e/kg). Launch Q4 2026.

Target collagen boost

≥25%

vs baseline (COL1A1/COL3A1)

Irritation reduction

Significantly lower

vs 0.3% retinol

Wrinkle reduction target

20% @ 8 weeks

Clinical target

Carbon footprint

<3 kg CO₂e/kg

Sustainability target

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Workflow pipeline

Customized for Bio-Retinol Fusion Complex™ requirements

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Drag-and-drop DAG

Branching: screening splits to manufacturability and prototyping.

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Stage details

1. Claim & Target Definition

Define retinol-like performance targets: collagen I & III ≥25% increase, fine line reduction, barrier repair (ceramides ↑, TEWL ↓), anti-inflammatory (IL-8, TNF-α reduction), radiance/tone uniformity. Map irritation-free pathway requirements.

Inputs

  • Primary claims: wrinkle reduction, radiance, firmness
  • Performance targets: ≥25% collagen boost, 20% wrinkle reduction @ 8 weeks
  • Irritation-free requirement vs retinol
  • Clean beauty compliance (Sephora Clean, Credo)

Outputs

  • Mechanistic target profile (RAR-independent pathways)
  • Irritation risk map vs retinol baseline
  • Claim validation roadmap

AI model

Choose/override per stage (demo).

Selected: Claim-to-Target Mapper

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Workflow runs

Execution history

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Key requirements

Performance & constraints

  • • ≥25% collagen boost (COL1A1/COL3A1)
  • • Irritation significantly lower than 0.3% retinol
  • • 12-month stability @ 40°C + light
  • • Clean formulation (no parabens, silicones, PEGs)
  • • pH 5.0–6.0 compatible